Vincencia_ Clinical Nutritionists

How Metformin Causes Vitamin B12 Problems and Nausea Metformin is a common diabetes medicine . One of its main side effects is nausea , especially when someone has just started taking it or is taking it on an empty stomach . It can also reduce the absorption of Vitamin B12 in the stomach. When B12 levels become low, it can worsen digestive symptoms like: Loss of appetite Stomach upset Nausea Slow B12 + Metformin irritation on the stomach = more nausea. How Passion 4 Life Helps Reduce the Nausea Passion 4 Life is a liquid multivitamin that is gentle on the stomach and contains Vitamin B12 plus other B-vitamins . It helps in three ways: 1️⃣ Replaces the Vitamin B12 Metformin Lowers This supports healthy nerves , energy and reduces B12-related nausea. 2️⃣ Liquid Formula = Easier Digestion Because it's liquid, it absorbs quickly without irritating the stomach like tablets or capsules. 3️⃣ Energy + Appetite Support  Many users feel less tired and more energized, which helps decre...

Managing Metformin-Induced Nausea and Vomiting: The Supportive Role of B-Vitamins in Clinical Practice with Passion For life  Metformin remains the cornerstone of Type 2 Diabetes Mellitus management worldwide. Its effectiveness, safety profile, and affordability make it the first-line therapy in most treatment guidelines. However, despite its benefits, gastrointestinal side effects particularly nausea and vomiting are frequently reported and remain a major barrier to optimal adherence, especially during treatment initiation or dose escalation. Why Does Metformin Cause Nausea and Vomiting? Metformin exerts significant effects within the gastrointestinal tract. High concentrations of the drug accumulate in the intestinal mucosa, increasing local glucose utilization and lactate production, which can irritate the gut lining. In addition, metformin delays gastric emptying and alters intestinal motility, leading to early satiety, nausea, and post-dose vomiting. The drug also influen...